| Text Copyright 2007 by Nancy Sculerati MD - all rights reserved | ||
| Cholesterol | ||
Cholesterol is a biochemical that is made in every human body, as well as in the bodies of most every animal. This fatty material is an important component in nerve sheaths, and many other vital parts of the body. Cholesterol deposits in arteries are part of a common disease process, however - and contribute to impaired blood flow in the limbs and heart muscle of people with atherosclerosis (a degeneration of the arteries). Atheroscerosis is thought to be the biggest contributor to coronary artery disease, which is the major killer in the USA of middle-aged and older adults.
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| Types of Human Cholesterol | ||
| Fatty cholesterol does not, by and large, float around "as is" in our blood. Instead, it is attached to proteins that transport it. These proteins are all of the kind called lipoproteins, lipo- being the prefix that indicates fats and lipids, and proteins being the large molecules that are made of amino acids.
When lipoproteins were frst identified in blood, they were noted to fractionate out in different layers of centrifuged blood samples, depending on how dense each layer was, that's actualy how many cell components and other biological molecules have also been separated from each other. The lowest density components float at the top in these spun tubes, the highest density items sink to the bottom - and the layers are a dependable way to purify each sort, or at least to begin the process of purification. |
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| HDL (High Density Lipoproteins) | ||
| LDL (Low Density Lipoproteins) | ||
| VLDL (Very Low Density Lipoproteins) | ||
| Cholesterol & Diet | ||
| Drugs that Lower Cholesterol | ||
| References | ||
| Liu J - Am J Cardiol - 15-NOV-2006; 98(10): 1363-8
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