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Q & A
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(adult brother with schizophrenia, what to do?)
My brother John's my burden now that our mother is dead. My younger brother wants nothing to do with him - been that way a long time. So that leaves me, the middle brother, in the middle. Its turn my back on John - or take care of him. I guess I'm his enabler. I know my mother was, no matter what, she kept him going, and I can't help but think it killed her in the end. John is 52, been schizophrenic for years and years. It's getting worse. He's getting worse. You know the story, they only take him at the hospital when he's so bad he's grabbed the wheel while I drove him there, and we ended up in the trees off the highway, and then - even then, he's out in a month - tops. Discharged. No warning, no call from the hospital that he's being discharged - he just shows up at my house, banging on the door. He has a monthly check, disability, good money, same money what I bring home after deductions, ...he blows it. I don't know where it goes. I call the hospital when he starts threatening, when he starts bringing drunks to the house, the hospital tells me to call 911. I've done that, and either nothing happens or the police come. If the police do come, either they back off and leave - do nothing, or tazer him and put him in handcuffs. I can't stand to see that, though once it's been so bad I stood there and watched them do it, and then thanked them for taking him, afterward. It killed my mother and now, I guess, it's gonna kill me. Are you an enabler? I don't think so. Being schizophrenic is not the same as being an alcoholic, even though your brother is also a substance abuser it's not like a 12 step program is all he needs. It's not like if you just showed him some tough love and stopped helping him survive he might just shape up and fly right. He is sick with a real illness, and that illness is more than you can handle. Schizophrenia |
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(altzheimers, death of a parent, could it have been prevented?)
My wife and I recently lost her father after a battle with Altzheimers. Even though we expected a long, slow process, the end seemed to come really quick, which made us wonder if there was an element of neglect in his loss. He had danced at my son's wedding one day and shortly after, while under the care of a family member, he began to refuse to eat. In less than a month, he had gone from 180 to 130 and became weak and emaciated. We got the phone call and he died two days later. We later found out that his blood suger had reached 480 as the family member had stopped giving him his glyberide (sp?). My question is this: Is this a normal progression of altzheimers or could the blood sugar problem have caused this sudden decline? I'm so sorry for your loss. Your love for your family shines out of your e-mail, as does the strength of your marriage. First off, when a parent dies suddenly, at least unexpectedly, it is normal to to feel, deep down, that it wasn't meant to be and somebody must have done something wrong. It was hard for me, my father died truly suddenly when I was a medical student - and I certainly felt that way, anyway - I blamed myself, for a time. Through reading and talking to my professors I came to see how usual it is to feel that "it doesn't make sense, if only..." Secondly, in terms of the medicine and the blood sugar: For sure, when a person who has any underlying medical issues, such as diabetes, has gone weeks without proper hydration and diet and medication and now is at the end-stage, the labs are not going to be normal.
That said, here you have presented him as being "well" and then refusing to eat. Let's examine that. Certainly, there are many reasons to refuse to eat that could have a physical cause, some intestinal problem, for example. But it is just as certain that many elderly people, or people with terminal illnesses "decide" to die and when that happens, close their mouths and resist food and drink.
From what I have seen as a physician, I'd say that there are several true answers to the "If he was treated differently could he have had more time?" question. Three of them, two are "yes" and one is "no" and all are different. Here they are:
So, if granted the supernatural ability to go back in time and change things, what would be the right thing to do? To have taken the father out of the care of the relative at the very first refusal to eat and put him in the care of a bunch of medical aces, and pushed them to go all out? Bring in "Dr. House" ?
One thing seems clear from your letter, it was he himself who stopped taking nourishment, who set off the chain of events. It may seem that he was well at the wedding, but dying people hold on to life in anticipation of such events as weddings of grandchildren, holidays, and anniversaries; and the fact that he danced at the wedding may not be so much a sign that he was doing well, as that he overcame his illness in triumph for that day. In such situations, rapid declines afterwards are exactly what usually happens. Could it be that after the wedding, he made up his mind that it was time?
Many people have thoughtful answers to that question - here's mine, again from my own experience in caring for patients for many years:
Again, it comes down to the question of whether it was right to 'let him be' instead of force nourishment and medical intervention against what seemed to be his will. Aggressive intervention might have changed things, perhaps for the better; and perhaps for the worse. In this situation, it is not clear that it would have prolonged his life or improved it. |
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(appendectomy, "spastic" colon, gas)
October 2, 2007 When I was 21 years old, I had major surgery to remove adhesions of the colon. At the same time, the doctor removed my healthy appendix, as well. That was more than 30 years ago, and in those days they did this procedure arbitrarily. Ever since, I've had a "spastic" intestinal tract with chronic gas (which inhibits my social life) and bloating. Is this condition related to my loss of appendix? If not, what? I've used every form of probiotic available and have eliminated sugars and starches, but nothing seems to help... J.M.C. Let's work through your question. From the history you give, we know for sure that you have had a problem with bloating and gas for years, since about age 21, and that it appeared after surgery on your abdomen. That surgery was, as far as you know, done to remove adhesions; and at the same time an "incidental appendectomy" was performed.
oops, I've wandered from your question, let's get back: Now, in terms of the appendix, professors of medicine say, "never say 'never' "; but I am willing to say (despite being that kind of professor, myself-) the appendectomy is not a cause for your problem. An apendectomy, like any abdominal surgery, can result in adhesions - and yes, obstruction can be a problem from adhesions - but the kind of chronic problem you describe really is not that kind of thing, AT ALL. The chronicity of your complaints- which, unless I have misunderstood, have been basically steady for at least 30 years is not the like pattern of bowel obstruction from adhesions, which causes acute problems.
What we do know is that IBS usually starts between adolescence and the 40s, and that is twice as common among women as men. |
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(mold in the basement, penicillin allergy)
September 27, 2007 Dear Dr. Nancy, We had a flood in our basement last April. I wasn't too worried about it , until I noticed that things have stayed so damp down there that there is mold growing on the joists now. On the advice of a neighbor, I got the mold tested - and found out that one of the kinds growing is penicillin! I am highly allergic to penicillin, I once went into shock because of it. Am I in danger if I go into the basement? -SC- Penicillium spinulosum is a common indoor mold, and- although the natural product of one type is an antibacterial mycotoxin that is the antibiotic called penicillin, there are no clear reports of especially severe reactions to environmental Penicillium by people allergic to the drug.
The risk of developing asthma, or an inflammation of the lungs, from breathing the air in your basement is very real, and other allergic reactions - including anaphylaxis are possible. So, yes- you are in danger in the basement and further- the mold in the basement can spread upward into the house over time. It's important to get the basement dry, do what ever you have to do to keep it dry - and then to have mold removed. Bush RK, et al: The medical effects of mold exposure. J Allergy Clin Immunol - 01-FEB-2006; 117(2): 326-33 |
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August 23, 2007 (Liver Damage & Tyelenol) I noticed that the "fine print" on the Tylenol bottle says "may cause liver damage." What volume (frequency? over time?) of this would you have to take for it to be dangerous? -n-
So let's run the numbers, answer the question and then get into a discussion about why this remains a safe drug for the great majority of people and how you can be sure that you are in that group: What makes this a toxic drug is the particular pathway that breaks it down.
It's important to realize that - like the word "xerox" or "kinko" used for any kind of photo copy, the word "tyelenol" has made its way into American English as a synonym for acetaminophin, even though its not. You might dismiss that as just another case of "brand name versus generic name" of a drug, but you would be wrong to - and here's why: Acetaminophen is in hundreds of over-the-counter formulations, and there's a reason for that. It's a good pain reliever, and it lowers fever, and in small doses, really is a very helpful ingredient for symptom relief of colds and various general ills. However, even if a person knows that the dose of acetaminophen cannot be infinite- that there must be a strict upper limit, it's easy to somehow assume that acetaminophen in these formulations does not count, because somehow- it's not either" tyelenol" or a generic form of the over-the-counter drug tyelenol. In other words, that person is not on the look-out for acetaminophen as an ingredient in cough syrups, cold pills, or -for that matter, Percocet ands other prescription drugs. It is in all these things. There's another trap that catches people: drug and alcohol abuse. Once again, many people do not admit even to themselves that taking their friend's prescription pain medicine is drug abuse, or that drinking every day, let alone steadily on from lunch or dinner till they fall "asleep" (also called "passing out") is alcoholism - or at least, alcohol abuse. The trouble with that kind of denial is that the liver is affected even if the psyche is not. Drink alcohol and your digestive system absorbs it, rather rapidly it gets into the blood stream and builds up a certain level. But realize please, that the liver gets a whole load straight from the stomach and upper intestine, before it even gets into the blood, and so most people who drink several drinks every day have given their liver extra peak levels with every drink. Although liver cells can be steeped in alcohol and survive, at some point they do get damaged. Many people who regularly drink have somewhat abnormal liver function, and some have severe disease, even; few know it. In terms of the prescription pain drugs (prescribed for somebody else or taken in excess by the legitimate patient), some of those can effect the liver, true - but more importantly, many contain acetaminophen along with codeine or oxycodeine or other narcotics. So there are many "hidden sources" of so-called tyelenol [and let's not blame the tyelenol manufacturers for their success in making the names the same in our mind- it's acetaminophen]. |
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(Cholesterol, Lipitor & Wine - in progress)
Dear Dr. Nancy, My doctor recently put me on a low dose of Lipitor (10 mg). My total cholesterol was in the 280 range (with a good cholesterol of about 65). I am a 32 year old male, approximately 5'10" and 160 lbs. I exercise fairly regularly and eat well. My question is whether alcohol will impact the effectiveness of the Lipitor or have adverse side effects on the liver. The insert for the medicine indicated that any person who consumes more than two alcoholic drinks per day should consult their doctor. My doctor is aware that I typically consume two glass of wine every day or every other day. May I continue to have several glasses of wine per day while I am taking Lipitor? If so, is it problematic to exceed two glasses per day on occassion? Thank you in advance for your thoughts. P. Dear P., Clearly, it is prudent to follow the recommendations of any medication's insert. Now, 1-2 glasses and "several glasses" of wine a day actually covers a very big range of possible alcohol dose. How many glasses? How big are the glasses? What kind of wine? Are we really sticking with wine or is some of that cognac? ...and -of course, nobody can predict the exact effects of alcohol & Lipitor in your body, even if the precise dose of daily ethanol was specified. I understand that your alcohol ingestion is routine with meals, but daily alcohol is a potential problem for anyone, unless portion control is truly adhered to. What I can do is review the current medical literature to answer more general questions about the liver, alcohol, Lipitor and cholesterol. That should help give a general understanding of the issues. Before I do, I need to lay out a few basic facts and concepts. Here goes:
Now, what is known about Lipitor's side effects?
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August 20, 2007 Hi Nancy! I'm trying to convince my mom to get checked out to see if she'd be a good candidate for a cochlear implant. If you have any recent info on it, pls let me know. She's very healthy and in good shape, so i think she should do it now while she'd be in better shape for surgery. She remembers that you recommended the MD whom she went to when the original hearing loss was realized -- 8 years ago in FLA. HT I remember, too. At that time, she had a sudden hearing loss in one ear, and- as I recall, the other ear had fairly normal hearing. I understand that over the years, the "good ear" has become less good, and now it is hard for her in social situations. And she is nothing if not social ! Most of us figure that you'd have to have a big hearing loss, a true impairment or deafness in both ears to have a big problem hearing conversation. Not true.
Cochear Implant or Hearing Aid, or Other Device or Remedy?
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(How long is it ok to take birth control pills?)
August 2, 2007 Hi Nancy! I think this is one that we older adults have wondered: When I was younger, we were told to only use the birth control pill for two years at a time due to the increased risk of stroke. Now my daughter has been taking it for 6 years and seems to think that it she can continue as long as she wants. Is this a good idea? DM According to current medical textbooks in Gynecology, there is no absolute time limit on how many years birth control pills can be taken by women who do not have certain risk factors for stroke or heart attack. What are these risk factors?
So, has anything changed except the recommendations over the last few decades? Yes - 2 basic changes have occurred:
If she smokes, and has high blood pressure, has ever had a blood clot problem or inflamed veins- then birth control pills should be reconsidered - with her doctor, of course. Personally, even if under age 35 - birth control pills and smoking are not a smart combination in my opinion, and it's the smoking that should go - that move will serve her well all of her life. Bottom line: she's right. Unless she has one of these complicating risk factors, currently, there is no recognized time limit for staying on the pill. |
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(da Vinci Robot Assisted Laparoscopic Hysterectomy)
July 31, 2007 Dear Dr. Nancy: My gynecologist has offered to do a laparoscopically assisted vaginal hysterectomy—which he says I need because he cannot find a cause for my post-menopausal vaginal bleeding—using the Da Vinci robot. He says that it will be less traumatic on my body than standard laparoscopy and will allow me to heal in one-to-two weeks, rather than two-to-six weeks. He says I will have five small incisions in my abdomen which will be less traumatizing than the 4 incisions he would have used for regular laparoscopy. My question to you is that, as using this robot is relatively new, what questions should I ask him about the procedure, the risks, and the recovery? MW
mmmm...."hysterectomy by standard laparoscopy v. hysterectomy by robot-assisted laparoscopy" doesn't seem to be the issue here. The small incisions made for both sorts of laparoscopy are in the same ballpark - and would not account for a big difference in recovery time. But: It may be that your surgeon feels that the da Vinci Robot will give him better ability to do the entire procedure laproscopically, in other words, the real issue is: a "hysterectomy using conventional open surgery techniques v. a laparoscopic hysterectomy. The latter avoids a large abdominal incision (large relative to the small incisions made for laparoscopic procedures) and/or the more invasive cuts done by other routes also used to perform a traditional hysterectomy. This seems to be the key to the faster recovery that comes with laparoscopic surgery. It's a question of not disrupting the muscular body wall, do that - disrupt the muscles with a sizeable incisions and then, after the surgery is over, getting up and moving around is painful and difficult for the patient until the body wall repairs itself; and that takes weeks. There is no question that the recovery from an uncomplicated laparoscopic hysterectomy is faster and easier than from the conventional kind. However, there is also no question that an "uncomplicated hysterectomy" is much more likely to happen with standard surgery than with laparoscopic surgery in most surgeons' hands. Although, at this time in the USA, hysteroscopy (looking into the abdominal cavity at the uterus) is extremely common, actually performing the entire excision laparoscopically is not. Only about 10% of hysterectomies are performed that way. Generally, it is only the most experienced and adept laparoscopic surgeons who will do laparoscopic hysterectomy - and even in their hands, major complications like bladder or ureter trauma is significantly more common than with conventional surgery.That's because the laparoscopic surgery is so much more difficult. A laparoscopic excision of the uterus (hysterectomy) would not take 2-6 weeks for healing, but would be expected to take the lesser recovery period he mentioned, and that would be with or without the robot. In terms of your body, the effects of the incisions and instruments are more or less the same for laparoscopic surgery whether or not the robotic system is used. However, the suturing and other surgical manipulations that need to be done for a hysterectomy take something of a laproscopic technical ace to accomplish. The Da Vinci Robot allows the adequate surgeon to do the surgery laparoscopically - to do it as well as the rare technical star who is adept at laparoscopic hysterectomy "free-hand". In other words, it sounds like the choice is between a laparoscopic hysterectomy with the robot, and a conventional hysterectomy without it. So, what questions: 1) Confirm that this is the choice. 2) I think that generally it is wise to ask any surgeon who is using new and complicated equipment what his or her experience has been with it. Are they familiar and comfortable with it? I think too that it is reasonable to ask if there is any back-up plan. Is there a chance that he may elect to do the conventional procedure, anyway? Under what circumstances? 3) Knowing from our private discussion that your surgeon is a world expert in the sorts of problems that you are most concerned with, I think that his up-front discussion with you, telling you his plan, asking your permission is really commendable. 4) The cost of the surgery is probably higher with the Robot. That's certainly reported in the literature. I don't say that's not worth it- especially if it allows you to have a very significantly shorter recovery period. In that case, the cost to your body, in a sense, is cheaper with the robot-assisted laparoscopic surgery than conventional hysterectomy. However, double checking your insurance situation and your personal financial liability is probably a good idea. That's the kind of generally prudent planning that I, myself, never do- but the wisdom and advantages of doing so are pretty straightforward.
So, what's the Da Vinci robot? This is a very expensive system (more than a million US dollars) that is being sold by a company on a commercial basis. It is the latest and most advanced robotic surgical system available, and it allows the surgeon to see in 3 dimensions, to operate without a tremor, and to control mechanical manipulators that move the surgical instruments rather than use her own hands to move the instruments. For those of you who have never done surgery, please realize that the tip of the instrument does the work- the surgeon holds the handle. In laparoscopic surgery-those handles are so long that the surgeons sometimes refer to the instruments as "sticks:, and just like using a poker to move ashes around in a fireplace, that long handle can make moves at certain angles impossible. The robotic manipulators, in a sense, put the surgeons hand control inside the abdomen, and markedly improves the ability to manipulate tissue. (Scroll below to a link to a video of actual surgery) According to the recent medical literature, comparisons of surgery that does not require the removal of large masses or entire organs (like pyeloraplasty) is not clearly advantageous with the da Vinci robot. The experienced laproscopic surgeon who is adept at suturing with freely held instruments can probably do as well with or without the robot, and do it faster and cheaper without- at least that is the conclusion of one surgeon who compared a series of operations both ways. [Link RE. Bhayani SB. Kavoussi LR. A prospective comparison of robotic and laparoscopic pyeloplasty. [Comparative Study. Journal Article] Annals of Surgery. 243(4):486-91, 2006 Apr. UI: 16552199]. To quote the Urologist, Dr. Link, who performed the surgeries and wrote the paper: "The development and dissemination of robotic surgical tools, such as the da Vinci system (Intuitive Surgical, Inc., Sunnyvale, CA), have the potential to alter the way urologists approach complex laparoscopic reconstructive procedures. Proponents of da Vinci cite the device's 3-dimensional visualization, damping of tremor, and more sophisticated surgical tools with greater degrees of freedom than traditional laparoscopic instruments. Certainly, the device eases the technical challenge of intracorporeal suturing and may make reconstructive laparoscopic procedures more accessible to surgeons without extensive laparoscopic experience. There is mounting evidence that the da Vinci provides significant benefits during laparoscopic radical prostatectomy, particularly in shortening operating time and decreasing surgeon fatigue. The robot is not, however, without significant disadvantages as compared with traditional laparoscopy. These include greater expense and consumption of operating room resources. The purpose of this study is not to discourage the use of the da Vinci system for LP. Certainly, for surgeons unfamiliar with intracorporeal suturing, the robot may lower the learning curve for LP. Rather, this report should serve as a cautionary tale arguing against the indiscriminate application of the da Vinci based only on a perception that it should accelerate suturing. Our results suggest that, for surgeons facile with intracorporeal suturing, dependence on the da Vinci robot adds little speed or quality advantage to the LP procedure and results in substantially greater costs". However, with hysterectomy - an altogether different procedure, the literature supports the notion that laparoscopic hysterectomy (without the robotic system) has the advantage of a short recovery time after the surgery, but the disadvantage of greater major complications. That's in the hands of the few surgeons who are comfortable doing laparoscopic hysterectomy. SEE VIDEO of laparoscopic hysterectomy using the da Vinci Robot The above linked video is surgery performed by the first author, Dr. Advincula, of the first of the papers referenced below:
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July 31, 2007 Dear Dr. Nancy, I've just finished fifteen months of chemotherapy following a lumpectomy and axillary node disection (21 nodes removed) for breast cancer (her2new, stage 3). I came through pretty well, but am feeling quite tired. How long before my energy comes back, and what's the best way to get back into exercise? Should I see a physical therapist first for advice on whether and when I can begin weight training? I don't want to aggrivate the slight lymphedema I have under my arm. Thanks. MM Dear MM, Such an important and reasonable question! - but one I can't answer directly, as much as I wish that I could. I just don't know. What I can do is review the published medical literature and see what I can find in terms of the record of other people's experience in similar situations. Here goes: First off, fatigue has long been recognized by oncologists (physicians specializing in cancer treatment) as being a notable feature in their patients, and has been documented in in breast cancer survivors for fifty years. "Patients with cancer frequently report that fatigue begins with cancer treatment—or even during the stressful diagnostic process—continues during the course of active cancer treatment, and declines when treatment is over. The fatigue may persist after treatment at a higher-than-baseline level, and a significant percentage of disease-free survivors report disruptive levels of fatigue for years after treatment. For example, in a survey of 1957 survivors of breast cancer, a third reported severe and persistent fatigue 3 years after diagnosis." That quote is from the textbook: Abeloff: Clinical Oncology, 3rd ed. Copyright © 2004 Churchill Livingstone, An Imprint of Elsevier As a rough guide, I think it is fair to think of cytotoxic chemotherapy (which literally translates as "cell killing" chemotherapy) as the kind that makes hair fall out. Now, today, much of the chemotherapy for breast cancer is not "cytotoxic", but hormonal - aimed at reducing growth factors for tumor cells that thrive on estrogen. Additionally, many people get both kinds of chemotherapy for breast cancer - in multiple courses, usually, the cytotoxic kind comes first. The article Fatigue in "Cancer Patients" discusses some details of what is known about patterns of fatigue during chemotherapy, and in people who have had radiation therapy. Let's get back to you - therapy is over, and - as far as anyone can tell, so is the tumor. The fatigue you report is recognized to be a frequent occurrence in cancer survivors, what is not recognized are the reasons for it. One of the more pursuasive theories is that the regulation of the physiologic response to acute stress is blunted in those cancer survivors who experience chronic fatigue. However, the chemical system that regulates inflammation in the body, the cytokine system is extra-sensitive and hyperactive. Bower JE. Ganz PA. Aziz N. Altered cortisol response to psychologic stress in breast cancer survivors with persistent fatigue. [Comparative Study. Journal Article. Research Support, N.I.H., Extramural. Research Support, Non-U.S. Gov't. Research Support, U.S. Gov't, P.H.S.] Psychosomatic Medicine. 67(2):277-80, 2005 Mar-Apr. UI: 15784794 Finally, what about the edema under the arm? Which therapies have been helpful in decreasing lymphedema of the arm, at least according to the published English-language peer-reviewed literature in Medicine and the Health Sciences? Well, in France, a treatment called "decongestion" is used routinely, at least in so far as I can tell from this article:
Interestingly, its first author is a Parisian physician who is part of the "Department of Lymphology" [Department of Lymphology, Hopital Cognacq-Jay, Site Broussais, 102 rue Didot, 75014 Paris, France e-mail: stephane.vignes@hopital-cognacq-jay.fr (Vignes, Arrault)] There is no sort of corresponding department in the United States - to my knowlege. This paper describes the course of over 500 patients treated for one year in just one of the "lymphology units" in that hospital. Again, I know of no center of this magnitude in the USA that concentrates on lymphedema, and suspect that this may be a tremendously valuable resource for patients who are able to visit Paris. The paper describes both physical therapy- usually given in the firt year post-op - and some compression bandages used to prevent lymphedema from worsening, over the long term. I realize that your major concern at the moment is "energy level" and that the arm swelling appears minor, but it strikes me that a center like this one might well have additional resources for its patients that might be helpful in restoration of full activity levels. Of course, the personnel at that center might know of similar centers in other French cities outside of Paris, but I do not know of any similar resources in our country. Meneses KD. McNees MP. Upper extremity lymphedema after treatment for breast cancer: a review of the literature. [Review] [86 refs] [Journal Article. Research Support, N.I.H., Extramural. Review] Ostomy Wound Management. 53(5):16-29, 2007 May. Moseley AL. Carati CJ. Piller NB. A systematic review of common conservative therapies for arm lymphoedema secondary to breast cancer treatment. [Review] [61 refs] [Journal Article. Review] Annals of Oncology. 18(4):639-46, 2007 Apr. |